ENVIRONMENTAL DETERMINANTS AND CONDITIONS OF THE DEVELOPMENT OF ENDEMIC GOITER
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Abstract
Endemic goiter remains a significant public health concern in geographically constrained regions where environmental iodine availability is limited. This study aims to analyze the etiopathogenesis of endemic goiter through an integrated environmental and biological framework. A systematic review and analytical synthesis of existing literature were conducted to evaluate the role of geochemical, nutritional, and ecological determinants in disease development. The findings indicate that iodine deficiency alone does not fully explain the persistence of endemic goiter; rather, it emerges from a complex interaction between environmental constraints and adaptive physiological responses. The study highlights the necessity of region-specific preventive strategies.
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References
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UNICEF. Micronutrient deficiency reports
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